diff --git a/rq/job.py b/rq/job.py
index 81ed98e..0dcbf28 100644
--- a/rq/job.py
+++ b/rq/job.py
@@ -254,12 +254,17 @@ class Job:
 
         # dependency could be job instance or id, or iterable thereof
         if depends_on is not None:
-            if isinstance(depends_on, Dependency):
-                job.enqueue_at_front = depends_on.enqueue_at_front
-                job.allow_dependency_failures = depends_on.allow_failure
-                depends_on_list = depends_on.dependencies
-            else:
-                depends_on_list = ensure_list(depends_on)
+            depends_on = ensure_list(depends_on)
+            depends_on_list = []
+            for depends_on_item in depends_on:
+                if isinstance(depends_on_item, Dependency):
+                    # If a Dependency has enqueue_at_front or allow_failure set to True, these behaviors are used for
+                    # all dependencies.
+                    job.enqueue_at_front = job.enqueue_at_front or depends_on_item.enqueue_at_front
+                    job.allow_dependency_failures = job.allow_dependency_failures or depends_on_item.allow_failure
+                    depends_on_list.extend(depends_on_item.dependencies)
+                else:
+                    depends_on_list.extend(ensure_list(depends_on_item))
             job._dependency_ids = [dep.id if isinstance(dep, Job) else dep for dep in depends_on_list]
 
         return job
diff --git a/tests/test_dependencies.py b/tests/test_dependencies.py
index 26b115d..980e805 100644
--- a/tests/test_dependencies.py
+++ b/tests/test_dependencies.py
@@ -117,6 +117,19 @@ class TestDependencies(RQTestCase):
         self.assertEqual(q.job_ids, ["fake_job_id_2", "fake_job_id_1"])
 
 
+    def test_dependency_list_in_depends_on(self):
+        """Enqueue with Dependency list in depends_on"""
+        q = Queue(connection=self.testconn)
+        w = SimpleWorker([q], connection=q.connection)
+
+        # enqueue dependent job when parent successfully finishes
+        parent_job1 = q.enqueue(say_hello)
+        parent_job2 = q.enqueue(say_hello)
+        job = q.enqueue_call(say_hello, depends_on=[Dependency([parent_job1]), Dependency([parent_job2])])
+        w.work(burst=True)
+        self.assertEqual(job.get_status(), JobStatus.FINISHED)
+
+
     def test_dependencies_are_met_if_parent_is_canceled(self):
         """When parent job is canceled, it should be treated as failed"""
         queue = Queue(connection=self.testconn)