diff --git a/rq/queue.py b/rq/queue.py
index 38aa05f..8d01e75 100644
--- a/rq/queue.py
+++ b/rq/queue.py
@@ -260,24 +260,26 @@ class Queue(object):
                                  description=description, depends_on=depends_on,
                                  job_id=job_id, at_front=at_front)
 
-    def enqueue_job(self, job, at_front=False):
+    def enqueue_job(self, job, pipeline=None, at_front=False):
         """Enqueues a job for delayed execution.
 
         If Queue is instantiated with async=False, job is executed immediately.
         """
-        with self.connection._pipeline() as pipeline:
-            # Add Queue key set
-            self.connection.sadd(self.redis_queues_keys, self.key)
-            job.set_status(JobStatus.QUEUED, pipeline=pipeline)
+        pipe = pipeline if pipeline is not None else self.connection._pipeline()
 
-            job.origin = self.name
-            job.enqueued_at = utcnow()
+        # Add Queue key set
+        pipe.sadd(self.redis_queues_keys, self.key)
+        job.set_status(JobStatus.QUEUED, pipeline=pipe)
 
-            if job.timeout is None:
-                job.timeout = self.DEFAULT_TIMEOUT
-            job.save(pipeline=pipeline)
+        job.origin = self.name
+        job.enqueued_at = utcnow()
 
-            pipeline.execute()
+        if job.timeout is None:
+            job.timeout = self.DEFAULT_TIMEOUT
+        job.save(pipeline=pipe)
+
+        if pipeline is None:
+            pipe.execute()
 
         if self._async:
             self.push_job_id(job.id, at_front=at_front)
@@ -289,15 +291,20 @@ class Queue(object):
         # TODO: can probably be pipelined
         from .registry import DeferredJobRegistry
 
-        registry = DeferredJobRegistry(self.name, self.connection)
-
         while True:
             job_id = as_text(self.connection.spop(job.dependents_key))
             if job_id is None:
                 break
             dependent = self.job_class.fetch(job_id, connection=self.connection)
-            registry.remove(dependent)
-            self.enqueue_job(dependent)
+            registry = DeferredJobRegistry(dependent.origin, self.connection)
+            with self.connection._pipeline() as pipeline:
+                registry.remove(dependent, pipeline=pipeline)
+                if dependent.origin == self.name:
+                    self.enqueue_job(dependent, pipeline=pipeline)
+                else:
+                    queue = Queue(name=dependent.origin, connection=self.connection)
+                    queue.enqueue_job(dependent, pipeline=pipeline)
+                pipeline.execute()
 
     def pop_job_id(self):
         """Pops a given job ID from this Redis queue."""
diff --git a/tests/test_job.py b/tests/test_job.py
index 6971d7b..1c92d84 100644
--- a/tests/test_job.py
+++ b/tests/test_job.py
@@ -5,7 +5,7 @@ from __future__ import (absolute_import, division, print_function,
 from datetime import datetime
 import time
 
-from tests import RQTestCase
+from tests import RQTestCase, fixtures
 from tests.helpers import strip_microseconds
 
 from rq.compat import PY2, as_text
@@ -16,7 +16,7 @@ from rq.registry import DeferredJobRegistry
 from rq.utils import utcformat
 from rq.worker import Worker
 
-from . import fixtures
+
 
 try:
     from cPickle import loads, dumps
diff --git a/tests/test_queue.py b/tests/test_queue.py
index bebdac7..5d87ddf 100644
--- a/tests/test_queue.py
+++ b/tests/test_queue.py
@@ -350,6 +350,45 @@ class TestQueue(RQTestCase):
         # DeferredJobRegistry should also be empty
         self.assertEqual(registry.get_job_ids(), [])
 
+
+    def test_enqueue_dependents_on_multiple_queues(self):
+        """Enqueueing dependent jobs on multiple queues pushes jobs in the queues
+        and removes them from DeferredJobRegistry for each different queue."""
+        q_1 = Queue("queue_1")
+        q_2 = Queue("queue_2")
+        parent_job = Job.create(func=say_hello)
+        parent_job.save()
+        job_1 = q_1.enqueue(say_hello, depends_on=parent_job)
+        job_2 = q_2.enqueue(say_hello, depends_on=parent_job)
+
+        # Each queue has its own DeferredJobRegistry
+        registry_1 = DeferredJobRegistry(q_1.name, connection=self.testconn)
+        self.assertEqual(
+            set(registry_1.get_job_ids()),
+            set([job_1.id])
+        )
+        registry_2 = DeferredJobRegistry(q_2.name, connection=self.testconn)
+        self.assertEqual(
+            set(registry_2.get_job_ids()),
+            set([job_2.id])
+        )
+
+        # After dependents is enqueued, job_1 on queue_1 and
+        # job_2 should be in queue_2
+        self.assertEqual(q_1.job_ids, [])
+        self.assertEqual(q_2.job_ids, [])
+        q_1.enqueue_dependents(parent_job)
+        q_2.enqueue_dependents(parent_job)
+        self.assertEqual(set(q_1.job_ids), set([job_1.id]))
+        self.assertEqual(set(q_2.job_ids), set([job_2.id]))
+        self.assertFalse(self.testconn.exists(parent_job.dependents_key))
+
+        # DeferredJobRegistry should also be empty
+        self.assertEqual(registry_1.get_job_ids(), [])
+        self.assertEqual(registry_2.get_job_ids(), [])
+
+
+
     def test_enqueue_job_with_dependency(self):
         """Jobs are enqueued only when their dependencies are finished."""
         # Job with unfinished dependency is not immediately enqueued